The first paper from our lab is now out in PLOS Pathogens! We created a panel of ACE2 variant cells and found that (pseudo)viruses with SARS-CoV spike, or the WT or N501Y SARS-CoV-2 spikes, differentially use the ACE2 protein surface during entry. This was a team effort, with Nidhi and Sarah on pseudotyped virus assays and molecular cloning, with Anna and Vini performing the BSL3 SARS-CoV-2 work. Great job, everyone!

The first paper from our lab is now out in PLOS Pathog! (https://t.co/uo9Q6U2naA). We created a panel of ACE2 variant cells and found that (pseudo)viruses with SARS-CoV spike, or the WT or N501Y SARS-CoV-2 spikes, differentially use the ACE2 protein surface during entry. [1/5] pic.twitter.com/egTPLoJ6LA

— Kenneth Matreyek (@kmatreyek) July 16, 2021